CTLA-4 ANTIBODY-DRUG CONJUGATE REVEALS AUTOLOGOUS DESTRUCTION OF B-LYMPHOCYTES ASSOCIATED WITH REGULATORY T CELL IMPAIRMENT

CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment

Germline CTLA-4 deficiency causes Front Selector Housing severe autoimmune diseases characterized by dysregulation of Foxp3+ Tregs, hyper-activation of effector memory T cells, and variable forms autoimmune cytopenia including gradual loss of B cells.Cancer patients with severe immune-related adverse events (irAE) after receiving anti-CTLA-4/PD-1 c

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Loosing Your Best Talent: Can Leadership Retain Employees? The Dilemma of the Banking Sector of Hyderabad Sindh, Pakistan: A Mediation Investigation

Country Super Fruits expects that commercial banking systems contribute to the overall development, but this development depends upon qualified and competent employees of the commercial banks institutions.Retaining this resource is of utmost importance for higher commercial banks.However, commercial banks are finding it hard to retain competent and

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